For researchers and pharmaceutical developers, Cortexolone 17alpha-propionate (CAS 19608-29-8) represents a critical compound in the study of androgen-related dermatological conditions. Marketed under names like Clascoterone and CB-03-01, this topical anti-androgen has gained traction for its efficacy in treating acne and hair loss. However, sourcing high-purity Cortexolone 17alpha-propionate at competitive prices requires navigating a complex landscape of suppliers, regulations, and quality assurances. This guide reveals how to secure the best deals while ensuring compliance and reliability.
What Is Cortexolone 17alpha-Propionate?
Cortexolone 17alpha-propionate is a synthetic steroid derivative that selectively inhibits androgen receptors in the skin. Its chemical structure allows it to block hormones like dihydrotestosterone (DHT) locally, reducing sebum production and inflammation without systemic side effects. Key applications include:
- Acne vulgaris treatment: FDA-approved as Winlevi® Cream 1%.
- Androgenetic alopecia research: Targets scalp DHT to slow hair thinning.
- Hormonal dermatology studies: Explores therapies for hirsutism and hormonal acne.
With a CAS registry number 19608-29-8, this compound is uniquely identifiable, ensuring precision in procurement and research reproducibility.
Why Cortexolone 17alpha-Propionate Is in High Demand
1. Non-Antibiotic Acne Solution
Unlike antibiotics, Cortexolone 17alpha-propionate reduces acne without contributing to bacterial resistance—a growing concern in dermatology.
2. Dual Therapeutic Potential
Clinical trials highlight its dual role in acne and hair loss, making it a versatile candidate for multifunctional skincare formulations.
3. Research Versatility
Its mechanism of action is valuable for studying androgen receptor pathways in vitro and in vivo, attracting academic and commercial labs alike.
Challenges in Sourcing High-Quality Cortexolone 17alpha-Propionate
1. Purity Concerns
Impurities in synthetic compounds can skew research results. Look for suppliers providing ≥98% purity verified by HPLC or NMR.
2. Counterfeit Products
Unregulated vendors may sell mislabeled or diluted products. A 2023 study found that 28% of online research chemicals failed purity tests.
3. Regulatory Compliance
Cortexolone 17alpha-propionate’s status varies globally:
- USA: Legal for research with proper documentation.
- EU: Requires REACH compliance for bulk imports.
- Asia: Subject to local pharmaceutical regulations.
4. Temperature Sensitivity
Improper storage during shipping can degrade the compound. Suppliers must use cold-chain logistics for stability.
How to Identify Reliable Suppliers
1. Certifications Matter
Prioritize suppliers with:
- GMP/ISO Certification: Ensures production in regulated facilities.
- Third-Party Testing: Independent labs validate purity and composition.
- Transparent COAs: Certificates of Analysis (COAs) should detail batch-specific data.
2. Evaluate Customer Support
Reputable vendors offer:
- Technical Guidance: Protocols for storage, solubility (e.g., in DMSO), and dosage.
- Responsive Communication: Email, phone, or live chat support for urgent queries.
3. Check Reviews and Credibility
Search for testimonials on platforms like ResearchGate or LabWorm. Avoid suppliers with vague or unverified claims.
Why Choose KiloBio for Cortexolone 17alpha-Propionate?
When quality and affordability intersect, KiloBio’s Cortexolone 17alpha-propionate (CAS 19608-29-8) stands out. Here’s why researchers trust us:
- Uncompromised Purity: Each batch undergoes HPLC testing, guaranteeing ≥99% purity.
- Competitive Pricing: Direct-from-lab pricing eliminates middlemen markups.
- Global Compliance: Pre-packaged with MSDS sheets and customs documentation for seamless international shipping.
- Bulk Order Flexibility: Discounts available for orders above 10g, ideal for long-term studies.
👉 Inquire About Cortexolone 17alpha-Propionate Pricing
FAQs About Purchasing Cortexolone 17alpha-Propionate
1. Is a Prescription Required to Buy Cortexolone 17alpha-Propionate?
For research use, no prescription is needed. Commercial or clinical applications may require regional approvals.
2. How Should I Store This Compound?
Store at 2–8°C in airtight containers. Avoid exposure to light and humidity.
3. Can I Use It in Combination with Other Actives?
Yes! It’s often paired with retinoids or minoxidil in experimental protocols. Consult published studies for synergies.
4. What’s the Typical Lead Time for Orders?
Most orders ship within 24–48 hours. USA deliveries take 3–5 days; international shipments require 7–14 days.
Tips for Securing the Best Deals
- Bulk Purchases: Save up to 30% on orders over 50g.
- Seasonal Discounts: Subscribe to supplier newsletters for holiday sales.
- Sample Testing: Request a 1g sample to verify quality before bulk orders.
Final Thoughts
Sourcing Cortexolone 17alpha-propionate (CAS 19608-29-8) demands a balance of cost-efficiency and quality assurance. By partnering with certified suppliers like KiloBio, you gain access to research-grade material that meets stringent regulatory and scientific standards.
Ready to Order? Contact KiloBio for personalized quotes and expedited shipping options.
