Fmoc-L-alanine is a critical reagent in peptide synthesis, but its cost can vary wildly between suppliers—especially when purchasing in bulk. Overpaying for subpar quality or hidden fees can drain your research budget and delay projects. Whether you’re scaling up drug discovery or managing a high-throughput lab, understanding how to secure Fmoc-L-alanine bulk price discounts is essential.
In this guide, we’ll break down pricing trends, compare top suppliers, and share actionable strategies to help you save without compromising quality. Plus, discover why Kilobio stands out as a cost-effective, reliable source for Fmoc-L-alanine (CAS 35661-39-3).
What is Fmoc-L-Alanine?
Fmoc-L-alanine (9-Fluorenylmethoxycarbonyl-L-alanine) is a protected amino acid used in solid-phase peptide synthesis (SPPS). The Fmoc group shields the amine terminus during chain assembly, enabling precise, stepwise elongation of peptides. Applications include:
- Therapeutic peptide development (e.g., antibiotics, hormones).
- Biomaterials engineering (e.g., self-assembling peptides).
- Academic research (e.g., studying protein folding).
With CAS 35661-39-3, it’s standardized for purity (≥98%) and stability. However, prices fluctuate based on supplier reputation, quantity, and quality guarantees.
Key Factors Influencing Fmoc-L-Alanine Pricing
1. Purity and Certification
Suppliers offering HPLC-verified purity (≥98%) with ISO 9001 or cGMP certifications often charge a premium. However, this ensures consistency and minimizes synthesis failures.
2. Order Quantity
Bulk purchases (100g to 1kg+) typically unlock discounts of 10–30%. For example, Kilobio’s Fmoc-L-alanine offers tiered pricing for industrial-scale orders.
3. Supplier Type
- Manufacturers: Direct suppliers like Kilobio cut middlemen costs.
- Distributors: Third-party vendors add markups but may offer faster shipping.
4. Shipping and Storage
Temperature-controlled logistics and airtight packaging prevent degradation but increase costs.
Fmoc-L-Alanine Price Comparison: Top 5 Suppliers (2025)
1. Kilobio
Kilobio combines competitive pricing with uncompromising quality:
- Bulk Discounts: Save up to 25% on orders over 500g.
- Transparency: Instant access to certificates of analysis (CoA).
- Global Reach: Affordable shipping to North America, Europe, and Asia.
- Custom Orders: Tailored quantities (1g to 10kg) and packaging.
Sample Pricing:
- 10g: $45
- 100g: $380 (15% off)
- 500g: $1,650 (25% off)
Why Choose Kilobio?
As a direct manufacturer, Kilobio avoids distributor markups and guarantees batch-to-batch consistency. Their Fmoc-L-alanine is ideal for academic and industrial labs prioritizing cost-efficiency.
Submit an Inquiry: Contact Kilobio for a personalized bulk quote.
2. Sigma-Aldrich (Merck)
- Pricing:
- 10g: $65
- 100g: $550
- Pros: Reliable quality, fast shipping.
- Cons: 20–30% pricier than niche manufacturers.
3. Bachem AG
- Pricing:
- 10g: $70
- 100g: $600
- Pros: Pharma-grade for GMP compliance.
- Cons: High minimum order quantities (MOQs).
4. ChemPep Inc.
- Pricing:
- 10g: $50
- 100g: $420
- Pros: Budget-friendly for small-scale orders.
- Cons: Limited bulk discounts.
5. Thermo Fisher Scientific
- Pricing:
- 10g: $60
- 100g: $500
- Pros: Bundle deals with resins/solvents.
- Cons: Subscription required for best rates.
3 Strategies to Secure Bulk Price Discounts
1. Negotiate Directly with Manufacturers
Suppliers like Kilobio often customize pricing for repeat clients or large orders. Ask about:
- Volume-based tiered discounts.
- Long-term supply agreements.
- Payment terms (e.g., net-30).
2. Compare CoAs Closely
Cheaper options may compromise purity. Always request recent certificates of analysis to verify:
- Purity (≥98% by HPLC).
- Residual solvent levels (e.g., <0.1% TFA).
3. Leverage Seasonal Promotions
Many suppliers offer quarterly sales (e.g., Q4 budget clearance). Sign up for newsletters or follow Kilobio’s product page for updates.
Risks of Choosing the Cheapest Supplier
While saving money is important, ultra-low-cost Fmoc-L-alanine can lead to:
- Low Coupling Efficiency: Impurities hinder peptide elongation.
- Batch Variability: Inconsistent results across experiments.
- Hidden Costs: Re-runs, delayed timelines, and wasted resources.
Stick to trusted suppliers like Kilobio that balance affordability with proven quality.
FAQs: Fmoc-L-Alanine Bulk Purchases
Q: What’s the typical lead time for bulk orders?
A: Most suppliers, including Kilobio, ship within 3–5 business days for in-stock items.
Q: Can I request custom packaging for moisture-sensitive reagents?
A: Yes. Kilobio offers argon-flushed, desiccated vials for hygroscopic compounds.
Q: Do bulk discounts apply to international orders?
A: Yes, but confirm shipping costs and import taxes upfront.
Why Kilobio Delivers Unmatched Value
As a specialized manufacturer, Kilobio invests in:
- Advanced QC Labs: Every batch undergoes HPLC, NMR, and MS testing.
- Sustainability: Recyclable packaging and solvent recovery programs.
- Expert Support: Dedicated chemists assist with synthesis optimization.
Ready to Save on Fmoc-L-Alanine?
Don’t let inflated prices derail your research. Visit Kilobio’s Fmoc-L-alanine product page to request a bulk quote or discuss custom requirements. Their team responds within 24 hours to help you maximize savings without sacrificing quality.
