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Scalable LPPS for complex peptides and fragments—ideal for difficult sequences, long segments and high‑purity intermediates.
Convergent fragment coupling reduces step count and aggregation risk.
Solution‑phase conditions and solvent control improve solubility and kinetics.
High‑purity fragments for payloads, linkers or SPPS‑LPPS hybrids.
We design sequence‑appropriate strategies (Fmoc/tBu) with orthogonal protections, optimized coupling/deprotection, and sequence‑specific additives to deliver high purity at scale.
Fmoc/tBu chemistry for linear and long peptides (up to ~60 aa, sequence‑dependent)
On‑resin cyclization/disulfide formation and selective deprotection
Difficult motifs mitigation: pseudoproline, backbone protection, chaotropic agents
LPPS/hybrid steps for challenging segments
High-efficiency automated systems enabling precise, reproducible peptide synthesis at various scales.
PEG-based resins optimized for high-yield synthesis of long or complex peptide sequences.
Integrated purification, analytical confirmation, and lyophilization for final peptide formulation.
SPPS comme plateforme principale avec LPPS/hybride pour les séquences longues ou difficiles.
Amidation/acétylation, disulfures, agrafage, PEGylation, lipidation, colorants/biotine.
Options brutes → >98% ; poudre ou solution lyophilisée ; contrôle des sels/contre-ions.
Plaques personnalisées pour le criblage ; livrées en format 96 puits avec traçabilité.
Peptides marqués par des isotopes stables pour la protéomique et les flux de travail de quantification.
Identité par HPLC/UPLC et MS ; CoA/CoT ; rapports supplémentaires disponibles sur demande.
