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Scalable LPPS for complex peptides and fragments—ideal for difficult sequences, long segments and high‑purity intermediates.
Convergent fragment coupling reduces step count and aggregation risk.
Solution‑phase conditions and solvent control improve solubility and kinetics.
High‑purity fragments for payloads, linkers or SPPS‑LPPS hybrids.
We design sequence‑appropriate strategies (Fmoc/tBu) with orthogonal protections, optimized coupling/deprotection, and sequence‑specific additives to deliver high purity at scale.
Fmoc/tBu chemistry for linear and long peptides (up to ~60 aa, sequence‑dependent)
On‑resin cyclization/disulfide formation and selective deprotection
Difficult motifs mitigation: pseudoproline, backbone protection, chaotropic agents
LPPS/hybrid steps for challenging segments
High-efficiency automated systems enabling precise, reproducible peptide synthesis at various scales.
PEG-based resins optimized for high-yield synthesis of long or complex peptide sequences.
Integrated purification, analytical confirmation, and lyophilization for final peptide formulation.
SPPS als primair platform met LPPS/hybrid voor lange of moeilijke sequenties.
Amidatie/acetylatie, disulfiden, nieten, PEGylatie, lipidatie, kleurstoffen/biotine.
Ruw → >98% opties; gelyofiliseerd poeder of oplossing; zout/tegenion controle.
Aangepaste platen voor screening; geleverd in 96-wells formaten met traceerbaarheid.
Stabiele-isotoopgelabelde peptiden voor proteomics en kwantificeringsworkflows.
HPLC/UPLC en MS identiteit; CoA/CoT; aanvullende rapporten beschikbaar op aanvraag.
