If you’re working on peptide synthesis, you know that the quality of your reagents can make or break your results. Fmoc-Lys-OH.HCl (CAS 139262-23-0) is a critical component in Fmoc-based solid-phase peptide synthesis (SPPS), and using a high-quality, peptide synthesis-grade product is essential. In this guide, we’ll explore the best sources for peptide synthesis-grade Fmoc-Lys-OH.HCl in 2025, ensuring you get the purity and consistency your experiments demand.
What is Fmoc-Lys-OH.HCl?
Fmoc-Lys-OH.HCl, also known as Nα-Fmoc-L-lysine hydrochloride, is a protected amino acid derivative used to introduce lysine residues into peptides. Its CAS number is 139262-23-0, and it’s widely used in:
- Solid-phase peptide synthesis (SPPS)
- Antibody-drug conjugates (ADCs)
- Protein degradation targeting chimeras (PROTACs)
Key features of peptide synthesis-grade Fmoc-Lys-OH.HCl include:
- High purity (typically ≥98%)
- Low levels of impurities (e.g., free amino acids, residual solvents)
- Compatibility with Fmoc-based SPPS protocols
Why Peptide Synthesis Grade Matters
Using peptide synthesis-grade Fmoc-Lys-OH.HCl ensures:
- High yield: Impurities can reduce coupling efficiency and overall yield.
- Reproducibility: Consistent quality leads to reliable results.
- Minimized side reactions: High-purity reagents reduce the risk of unwanted byproducts.
Top Suppliers for Peptide Synthesis-Grade Fmoc-Lys-OH.HCl in 2025
Here’s a list of trusted suppliers offering high-quality, peptide synthesis-grade Fmoc-Lys-OH.HCl:
1. KiloBio
KiloBio is a leading supplier of biochemicals, including peptide synthesis-grade Fmoc-Lys-OH.HCl. They offer:
- High purity: Rigorous quality control ensures reliable performance.
- Competitive pricing: Affordable rates for both small and bulk orders.
- Fast shipping: Quick delivery to minimize downtime.
👉 Visit KiloBio’s product page to learn more and request a quote: Buy Fmoc-Lys-OH.HCl
2. Sigma-Aldrich
Sigma-Aldrich is a well-established name in the chemical industry, offering:
- Certificates of Analysis (CoA): Guarantees quality and consistency.
- Multiple packaging options: From milligrams to kilograms.
- Global availability: Easy access for labs worldwide.
3. ChemPep
ChemPep specializes in amino acids and peptide-building blocks, providing:
- Custom synthesis options: Tailored to your specific needs.
- Bulk discounts: Save on large orders.
- Technical support: Expert advice for your projects.
4. Bachem
Bachem is a global leader in peptide chemistry, offering:
- GMP-grade options: For pharmaceutical applications.
- Comprehensive documentation: Includes CoA and MSDS.
- Reliable shipping: Ensures timely delivery.
5. Alfa Chemistry
Alfa Chemistry is known for its extensive catalog of biochemicals, including:
- High-purity Fmoc-Lys-OH.HCl: Suitable for sensitive applications.
- Competitive pricing: Affordable options for academic and industrial labs.
- Customer support: Responsive and helpful service.
How to Verify Peptide Synthesis Grade Quality
When selecting a supplier for Fmoc-Lys-OH.HCl, consider the following factors:
1. Certificates of Analysis (CoA)
A CoA provides detailed information about the product’s purity, identity, and quality. Always request a CoA before making a purchase.
2. Impurity Levels
Ensure the supplier provides information on impurity levels, such as free amino acids and residual solvents.
3. Customer Reviews and Reputation
Look for reviews or testimonials from other researchers. A supplier with a strong reputation is more likely to provide reliable products.
4. Technical Support
Suppliers that offer technical support can help troubleshoot issues and provide guidance on product use.
Why Choose KiloBio for Peptide Synthesis-Grade Fmoc-Lys-OH.HCl?
KiloBio stands out as a top choice for peptide synthesis-grade Fmoc-Lys-OH.HCl due to:
- High-quality products: Rigorous quality control ensures reliable performance.
- Affordable pricing: Competitive rates for both small and bulk orders.
- Excellent customer service: Responsive support for inquiries and orders.
👉 Visit KiloBio’s product page to learn more and request a quote: Buy Fmoc-Lys-OH.HCl
Tips for Successful Peptide Synthesis
- Use high-quality reagents: Ensure all reagents, including Fmoc-Lys-OH.HCl, are peptide synthesis grade.
- Optimize coupling conditions: Adjust reaction conditions to maximize yield and minimize side reactions.
- Monitor progress: Use analytical techniques (e.g., HPLC) to track synthesis progress.
- Store reagents properly: Keep Fmoc-Lys-OH.HCl in a cool, dry place to maintain stability.
Conclusion
Finding the best sources for peptide synthesis-grade Fmoc-Lys-OH.HCl (CAS 139262-23-0) is essential for the success of your peptide synthesis projects. By choosing a trusted supplier like KiloBio, you can ensure high-quality reagents, competitive pricing, and reliable delivery.
👉 Ready to buy? Visit KiloBio’s product page here: Buy Fmoc-Lys-OH.HCl
